![]() 7–9Īllergens belong to a number of protein families. Children with SPT results above these levels are presumed to be clinically reactive to eggs, and there is no need to perform oral food challenges. SPT was performed with standard commercial extracts or with fresh egg for egg allergy a wheal size of 7 mm has a 95 percent positive predictive value (PPV) for children over two years of age and 5 mm has a 95 percent PPV for children two years or younger. SPT is a simple, safe, inexpensive and time-saving test for the evaluation of patients with food allergy. The diagnosis of HEA is usually based on the detailed history of allergic reaction supported by in vivo skin prick test (SPT) or in vitro serum-specific IgE tests. Oral food challenges are the gold standard to establish food allergy definitively. The major egg yolk protein is chicken serum albumin however, the egg yolk displays less allergenicity than the white. Hen’s egg white proteins constitute ovomucoid, ovalbumin, ovotransferrin, lysozyme, and ovomucin. The severity of symptoms varies from mild involvement in an organ to life-threatening anaphylaxis. 1,2 IgE-mediated reactions to chicken’s egg often occur within several minutes to two hours after ingestion, and symptoms are related to the skin, gastrointestinal tract and rarely to respiratory system. Hen’s egg allergy (HEA) is the main cause of IgE-mediated food allergy in 0.5–2.5 % of children younger than five years of age. Conclusionīecause of fewer sensitizations to some avian eggs, further research should clarify starting oral immunotherapy with the yolk of goose and pigeon in children with hen’s egg allergy. Skin tests of the control group were negative to all the tested extracts. The most frequent positive skin tests were related to quail’s white (36 = 69.2%) followed by duck’s white (34 = 65.5%), and sensitization was the least frequent in pigeon’s yolk (23 = 44.2%). Resultsįifty (96.1%) children with hen’s egg allergy showed positive sensitization to at least one of the avian eggs. Skin prick tests were performed in both patient and control groups with fresh extract of white and yolk related to pigeon, duck, goose, turkey, quail, and partridge. This cross-sectional study enrolled 52 infants with hen’s egg allergy and 52 healthy infants with no history of food allergy from October 2018 to April 2019. The aim of this study was to assess the clinical cross-reactivity of different birds ’ eggs in children with hen’s egg allergy based on skin prick test results. See moreĪ high rate of cross-reactivity has been reported between the specific proteins of hen’s egg with proteins of various avian eggs by quantitative immunoelectrophoretic techniques. Letters to the Editor on previously published papers are welcomed.Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology. Manuscripts related to clinical, epidemiological and experimental allergology and childhood immunopathology will be considered for publication. Allergologia et Immunopathologia is no longer published on Elsevier since the 2021 year.Transferred to Codon PublicationsĪllergologia et Immunopathologia is a forum for those working in the field of asthma, allergy and immunology related to childhood. ![]()
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